I've found CNS's simulated annealing composite omit maps to be very useful in situations like this to avoid phase bias. RESOLVE's prime and switch offers similar functionality, but I've had less experience with it.
ho UC Berkeley
I've found CNS's simulated annealing composite omit maps to be very useful in situations like this to avoid phase bias. RESOLVE's prime and switch offers similar functionality, but I've had less experience with it.
ho UC Berkeley