Research Associate in X-ray protein crystallography of light induced reactions
Employer:Imperial College London Website:http://www.imperial.ac.uk/mol... Location:Exhibition Road, South Kensington, London, SW7 2AZ Posted:October 21, 2009 Expires:January 04, 2010 Requisition number: NS2009160AB Salary: £26,720 – £38,930 per annum Fixed Term for 24 months Applications are invited for a Research Associate position in the Division of Molecular Biosciences in the field of time resolved Laue X-ray crystallography of light sensitive proteins in the group of Dr. Jasper van Thor. The successful candidate will develop and employ experiments for time resolved X-ray diffraction using the pink-Laue technique at specialised beam line stations that combine pulsed broadband hard X-rays with pulsed optical excitation, at the SLS, APS and ESRF. The post will be based at Imperial College London, South Kensington campus The work will be conducted in a multidisciplinary environment which includes facilities for ultrafast electronic and vibrational spectroscopies to support the optical control of photolysis and reaction initiation in macromolecular crystals. The research deals with the light induced reactions in photoreceptors and fluorescent proteins and will focus on crystallisation of existing and new targets, analysis and optimisation of Laue diffraction, data processing and structure calculation of sub-ns intermediates. The van Thor group also provides support for ultrafast spectroscopic investigation of light induced reactions in targets. You will be required to work with members of the team on spectroscopic characterisation and photolysis control. You will have a PhD in a relevant discipline (e.g. biochemistry, chemistry or physics) or the equivalent professional qualifications and experience with a track record in Structural Biology. You will have extensive experience in monochromatic and/or Laue protein X-ray crystallography using synchrotron beam line stations or alternatively neutron diffraction. You will also have experience in crystallographic data processing and structure calculation. Experience in biomolecular spectroscopy would be an advantage. Experience with molecular biology, protein purification and crystallisation will be desirable. Our preferred method of application is online via our website http://www3.imperial.ac.uk/employment. Please complete and upload an application form as directed.
