You have several companies out there that sell that.

You have
Enamine - large collection, good but....$$$$$,
Maybridge - good but....$$$$
Zenobia Inc - good, and not so  $$$$

leo

On 27 Oct 2009, at 14:58, c.weinert wrote:

Dear all.

I am looking for a library of small (biologically relevant) compounds to test binding to a protein. Does somebody know, if there is a company that sells such a library for fragment based library screening? (to a reasonable price).

And does anybody has experience with screening such libraries? I assume that one approach would be soaking the protein with the compounds, followed by SEC and MS analysis. Anybody tried directly soaking crystals followed by X-ray analysis?

Thanks alot already in advance for your help.

Sincerely,
Christopher

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