A company called ZoBio screens their 2,000 fragment library with NMR, cool technology. Don't know about €€€€€

www.zobio.com

Flip

Sridhar Prasad wrote:

Zenobia is a good place to look for, they can even customize it your needs.

www.*zenobiatherapeutics*.com

Sridhar

> Date: Wed, 28 Oct 2009 01:41:22 +0000
 > From: hlsilves...@gmail.com
 > Subject: Re: [ccp4bb] small molecule library
 > To: CCP4BB@JISCMAIL.AC.UK
 >
 > You have several companies out there that sell that.
 >
 > You have
 > Enamine - large collection, good but....$$$$$,
 > Maybridge - good but....$$$$
 > Zenobia Inc - good, and not so $$$$
 >
 > leo
 >
 > On 27 Oct 2009, at 14:58, c.weinert wrote:
 >
 > > Dear all.
 > >
 > > I am looking for a library of small (biologically relevant)
 > > compounds to test binding to a protein. Does somebody know, if there
 > > is a company that sells such a library for fragment based library
 > > screening? (to a reasonable price).
 > >
 > > And does anybody has experience with screening such libraries? I
 > > assume that one approach would be soaking the protein with the
 > > compounds, followed by SEC and MS analysis. Anybody tried directly
 > > soaking crystals followed by X-ray analysis?
 > >
 > > Thanks alot already in advance for your help.
 > >
 > > Sincerely,
 > > Christopher

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