11-Dec-2009   11:30 Rehovot
Dear All,

I Agree fully with Tommi, and feel, in parallel, we in the MX community must 
think of better tools for referees to review papers and insist that these be 
followed. For example we should insist on getting BOTH the coords and structure 
factors for papers submitted, so it would be possible to do test on the 
structures which appear to have 'question marks'. Without this data, it is very 
difficult to do a serious job in refereeing.

Also, any manuscript, submitted to any journal, where BOTH the structure 
factors and coords are not submitted to the PDB should be rejected immediately 
without further review. This should be the policy of the reviewer, independent 
of any particular policy of the journals.

It might be worthwhile for the MX community to also consider writing a strong 
letter to the journals in which published the papers for which the structures 
have now been retracted, to state just how serious this matter is and that the 
journals should also take much more responsibility of finding better ways to 
have these papers and structures reviewed.

Joel
-------------------------------------------------
Prof. Joel L. Sussman
Director, Israel Structural Proteomics Center
Dept. of Structural Biology
Weizmann Institute of Science
Rehovot 76100 ISRAEL

Tel: +972 8-934 4531
Fax: +972 8-934 6312
[email protected]
www.weizmann.ac.il/~joel; www.weizmann.ac.il/ISPC
-------------------------------------------------

On 11 Dec 2009, at 11:19, Tommi Kajander wrote:

> Would the exact analysis of how each of these things were wrong and 
> fabricated be somewhere
> available???? Would be fair (apart from the known case of C3b) to have the 
> whole analysis available
> instead of just this kind of news feed. I suspect its not obvious by five 
> minute check in all cases.
> 
> Perhaps there needs to be ways within PDB in form of automated tools that 
> would raise those red
> flags in suspicious cases (e.g. some data analysis --such as the contribution 
> by solvent etc now that data beyond 8Å
> is by default used in refinement) - as it appears peer review/editing by 
> journals isn't/cant always be(?) stringent enough.
> 
> In any case, some type of  automated analysis of the whole data base might be 
> a good idea, as there can be
> other cases (with another couple of thousand papers citing them..).
> 
> tommi
> 
> On Dec 10, 2009, at 4:16 PM, Ibrahim Moustafa wrote:
> 
>> "After a thorough examination of the available data, which included a
>> re-analysis of each structure alleged to have been fabricated, the committee
>> found a preponderance of evidence that structures 1BEF, 1CMW, 1DF9/2QID,
>> 1G40, 1G44, 1L6L, 2OU1, 1RID, 1Y8E, 2A01, and 2HR0 were more likely than not
>> falsified and/or fabricated and recommended that they be removed from the
>> public record," the university said in its statement this week."
> 

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