On Thu, Jul 29, 2010 at 8:25 PM, Pavel Afonine <[email protected]> wrote:
>
> Speaking of 3fo2fc or 5fo3fc, ... etc maps (see classic works on this
> published 30+ years ago), I guess the main rationale for using them in those
> cases arises from the facts that
>
> 2Fo-Fc = Fo + (Fo-Fc),
> 3Fo-2Fc = Fo +2(Fo-Fc)
>
> To be precise, it is actually
>
> 2mFo-DFc for acentric reflections
> and mFo for centric reflections

I prefer to think of it rather as

2mFo - DFc = DFc + 2(mFo-DFc)   for acentrics and
mFo = DFc + (mFo-DFc)               for centrics.

Then it also becomes clear that to be consistent the corresponding
difference map coefficients should be 2(mFo-DFc) for acentrics and
(mFo-DFc) for centrics.

Cheers

-- Ian

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