Hi Rex,

There will be small differences in particular due to the different ways of treating the solvent. How large of a difference are you talking about? Normally the difference should not be very large... And if this related to solvent effects, it will affect the low resolution reflections with a decrease in the effect when you go to higher and higher resolutions (but never completely disappear).

Fred.

REX PALMER wrote:
Does anyone still use CNS ?
Do we expect Rfree from CNS for example to be different from the value given by Refmac at the end of the refinement? Rex Palmer Birkbeck College

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