Trying to calculate a difference map from a dataset downloaded from the RCSB
and one I have.  The following applies:

Object find the difference between two bound ligands of the same structure
in the same space group.

My following work path has been:

1) Convert mmCIF to mtz (RCSB data set)
2) Use CAD to combine them
3) Use FFT to generate the diff map

If I remember correctly, I think I am missing a scaling step somewhere.
Any thoughts?

Scott



-- 
Scott D. Pegan, Ph.D.
Assistant Professor
Chemistry & Biochemistry
University of Denver
Office: 303 871 2533
Fax: 303 871 2254

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