Use robot. You only need 0.1ul*96=9.6ul of protein solution.



On Thu, Mar 3, 2011 at 7:59 PM, m zhang <[email protected]> wrote:

> Dear all,
>
> I am trying to optimize my crystal with additives. Since the yield of my
> protein purification is very limited, I am wondering what is the most
> efficient way to set up drops with additive to save my protein and not
> wasting additives? I am setting up 1 to 1 drops with 0.2 ul additives. But I
> feel 0.2ul is not very actuate, even if I use a p2.  Would you share your
> ways to set up drops with additives? If I want to screen some additives,
> what additives would you suggest to try first, especially those from the 96
> additive conditions from Hampton? By the way, just wondering, what kind of
> p2 pipettor work better? Any input is greatly appreciated!
>
> Thank you,
>
> Min
>

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