The program Pointless in CCP4 (Data reduction -> Find symmetry) will combine 
the files and average the unit cells. If they are very different you might have 
to increase the "tolerance", though you should then worry about whether it's 
sensible to combine them

Phil

On 16 May 2011, at 22:40, Md. Munan Shaik wrote:

> Dear all,
> Can anybody give me some suggestion about data processing with mosflm. I want 
> to process one dataset with defining the cell parameter. 
> I collect two dataset of the same crystal but when I am trying to index and 
> integrate then i saw some differences in the cell parameter. 
> 
> I also tried to combine two MTZ  with "sortmtz" but it fails. So, now I tried 
> to process second dataset with defining cell parameter from the previous one. 
> Please suggest me some ways.
> 
> thanks you in advance
> 
> regards
>  
> ===================================================
> Md. Munan Shaik
> Department of Biotehnology
> School of Bioscience and Biotechnology
> via G. Colombo 03
> Padova 35131, Italy
> 
> 
> 

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