[ccp4bb] Insoluble ligand?

[Chaudhary, Ritcha]

Hi All

I have a ligand that is dissolved in 100% DMSO. The ligand crashes out even 
when diluted to 20% final DMSO concentration in the protein buffer. I have 
heard of people using detergents such as n octyl Beta D glucoside to keep the 
ligand solubilized at lower DMSO concentrations. Can someone give me pointers 
in this direction? Any suggestions, references etc.....

Thanks much
Ritcha