Hi Xiaopeng,

If you are feeding both programs exactly the same file then you are not
doing anything wrong. Notice that, if you calculate the Ramachandran plot on
Molprobity and then you go on coot, do a round of manual refinement, and
only then calculate the Ramachandran, then that can be the source of the
difference. But I would bet that it is because different programs have their
own definition of what is allowed and what is an outlier.

I personally use the Ramachandran plot on coot just to guide my refinement,
but use another program (Molprobity is pretty good) to do a thorough
validation.

Good luck,

Mario Sanches

2011/9/30 Xiaopeng Hu <[email protected]>

> Dear all,
>
> I just notified that there is a big difference between the Ramachandran
> plot analysis results produced by Coot and Morprobity (or Phenix). For the
> structure I am working now, Phenix(Morprobity) gives out Ramachandran
> outliers 0.2%, favored 95.2%, whileas Coot gives out Outliers 1.24%, Allowed
> 5,14% and Prefered 93.62%.I am wondering if there is a simply explain for
> the difference which I don't know? Or I just made some silly mistakes?
>
> Best wishes,
>
> xiaopeng
>



-- 
Mario Sanches
Postdoctoral Researcher
Samuel Lunenfeld Research Institute
Mount Sinai Hospital
600 University Ave
Toronto - Ontario
Canada
M5G 1X5
http://ca.linkedin.com/in/mariosanches

Reply via email to