> Maybe it's just a sequencing glitch?

Not so--BLAST showed there are a whole cadre of these things in
various genomes. Go figure.

JPK





>
> JPK
>
>
> On Tue, Oct 4, 2011 at 4:05 PM, Jacob Keller
> <[email protected]> wrote:
>> Thanks everybody, I tried using
>>
>> --toolkit tuebingen mpi
>> --Scanprosite
>>
>> I think my regex syntax was different from the Tuebingen site's, but
>> scanprosite worked well and found many hits, although without really
>> hitting paydirt. I think both of these programs would do the job well,
>> though.
>>
>> Thanks very much for your speedy help (this BB is truly amazing!),
>>
>> Jacob
>>
>>
>>
>> On Tue, Oct 4, 2011 at 3:47 PM, David Briggs <[email protected]> 
>> wrote:
>>> Hi Jacob,
>>> SCAN PROSITE
>>> http://prosite.expasy.org/scanprosite/
>>> will do precisely what you want.
>>> C-X-C-X-C-X-C
>>> or
>>> C-X-C-X-C
>>> would be the pattern using Prosite syntax.
>>> Cheers,
>>> Dave
>>> ============================
>>> David C. Briggs PhD
>>> Father, Structural Biologist and Sceptic
>>> ============================
>>> University of Manchester E-mail:
>>> [email protected]
>>> ============================
>>> http://manchester.academia.edu/DavidBriggs (v.sensible)
>>> http://xtaldave.wordpress.com/ (sensible)
>>> http://xtaldave.posterous.com/ (less sensible)
>>> Twitter: @xtaldave
>>> Skype: DocDCB
>>> ============================
>>>
>>>
>>> On 4 October 2011 21:34, Jacob Keller <[email protected]>
>>> wrote:
>>>>
>>>> Dear Crystallographers,
>>>>
>>>> I cannot get BLAST to find all proteins with the motif cxcxcxc or at
>>>> least cxcxc. It seems to think of "x" as an actual amino acid rather
>>>> than a wildcard. There must be some easy way to do this? Ordinarily to
>>>> find a short motif, I would just paste the sequence and get the
>>>> answer, but here the C's are an absolute requirement and there is no
>>>> constraint on the x's except that they be only one residue.
>>>>
>>>> JPK
>>>>
>>>> --
>>>> *******************************************
>>>> Jacob Pearson Keller
>>>> Northwestern University
>>>> Medical Scientist Training Program
>>>> cel: 773.608.9185
>>>> email: [email protected]
>>>> *******************************************
>>>
>>>
>>
>>
>>
>> --
>> *******************************************
>> Jacob Pearson Keller
>> Northwestern University
>> Medical Scientist Training Program
>> cel: 773.608.9185
>> email: [email protected]
>> *******************************************
>>
>
>
>
> --
> *******************************************
> Jacob Pearson Keller
> Northwestern University
> Medical Scientist Training Program
> cel: 773.608.9185
> email: [email protected]
> *******************************************
>



-- 
*******************************************
Jacob Pearson Keller
Northwestern University
Medical Scientist Training Program
cel: 773.608.9185
email: [email protected]
*******************************************

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