We are looking for a research associate to join our group. If you have any questions, please contact me.
-Dirk Dirksen E. Bussiere, Ph.D., MBA Director, Structural Chemistry Novartis Institutes for BioMedical Research 4560 Horton Street, M/S 4.6 Emeryville, CA. 94608 USA dirksen.bussi...@novartis.com Scientific Associate I/II, Structural Chemistry Req. No. 87432BR NIBR - Novartis Emeryville, CA About Novartis Institute of Biomedical Research At Novartis Institutes for BioMedical Research (“NIBR”), the global research organization of Novartis, we are committed to discovering innovative medicines to cure disease and improve human health. By hiring the best academic, biotech, and pharmaceutical trained scientists, we have fostered and atmosphere for drug discovery where innovation is rewarded. It is ultimately the talent of the individual that determines our success, while our state-of-the-art technologies and resources enable these ideas to be realized. NIBR has sites in Cambridge, Massachusetts; Emeryville, CA; Basel, Switzerland; Horsham, UK; and Shanghai, China. Our Emeryville location focuses on early drug discovery efforts for the Oncology Disease Area and offers a variety of positions in Biology, Chemistry, and functions such as Technology, Patents, Research Sciences and other areas that support our scientific resources. About Structural Chemistry: The NIBR Emeryville Structural Chemistry group is responsible for actively pursuing the structures of macromolecular drug targets either as apo-proteins or in complex with lead compounds to help guide structure-based drug design, and actively participates in the drug discovery process. The group also provides biophysics and solutions studies support for drug discovery projects. Position Description: The qualified candidate will use his/her scientific expertise to aid in structure-based drug design efforts. Specifically, this individual will determine high-resolution, three-dimensional structures of macromolecular drug targets (typically proteins), including crystallization and structure solution of medically important structures and target-ligand complexes. Additionally, this individual will interact with computational chemists and medicinal chemists to design new scaffolds and improve lead compounds. Qualifications: Qualified candidates will have a BS/MS in Biochemistry, Chemistry, or Molecular Biophysics with at least 4 years of relevant work experience in protein biochemistry, protein crystallization, and crystallographic methods, pharmaceutical industry experience is a plus. Strong computational and molecular modeling skills, experience in solution studies (calorimetry, NMR, etc.) and/or experience in structure-based drug design is preferred, as is experience with membrane protein biochemistry and/or crystallization. Candidates should have excellent verbal and written communication skills and the ability to work in large, multidisciplinary project teams. To apply for this position, please visit: http://novartis.avature.net/jobs#ViewJob/94
