PDE2 full length versus domain only structures, I think.

Artem

On Thu, Jan 12, 2012 at 10:03 AM, Qiang Chen <[email protected]>wrote:

> Hi,
>
> I'm working on a multi-domain protein which uses three domains to form
> homodimer, and the full-length structure is available. We have solved the
> structure of one binding domain alone and found its homo-binding mode is
> totally different from that of the full-length protein.
>
> Do you know examples or papers discussing the similar subjects (crystal
> packing shows false binding mode)?
>
> Thanks a lot!
>
> Qiang
>
>
>
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