On 02/07/2012 08:31 AM, Dialing Pretty wrote:
Dear All,After we refine the structure of the protein to satisfactory with satisfactory Rwork and Rfree, we pick water by phenix refine, and I find Rfree always increases slightly after the water picking refinment. Do you have nay idea to solve this problem or any comment? Cheers, Dialing
Well - it shouldnt! Check if there is some problem.. Eleanor