On Fri, 2012-01-13 at 10:40 -0800, Ethan Merritt wrote:
> Which of these two statements would be more useful:
> 1) The RMSD for sidechain atoms between apo and holo was 0.678 Å.
> or
> 2) Only two residues exhibited a significant change of
> conformation:
Perhaps the same is true for the backbone. RMSD is uninterpretable in
general, since one collapses information about the distribution of
positional shifts of hundreds of atoms into one number. On the other
hand, looking at phi/psi angles helps to pinpoint the regions that
undergo conformational changes.
--
Hurry up, before we all come back to our senses!
Julian, King of Lemurs
