Dear Crystallographers, I am looking for references which discuss the validity of the assertion that multiple crystal structures of the same or similar proteins can be considered freeze-frame snapshots of actual conformations assumed in solution. In a way, the assertion seems almost definitely true to me, but on the other hand, I could imagine some objections as well. Seems there should be some classic literature here...
All the best, Jacob -- ******************************************* Jacob Pearson Keller Northwestern University Medical Scientist Training Program email: [email protected] *******************************************
