How could they not be snapshots of conformations adopted in solution? James
On Feb 10, 2012, at 1:25 PM, Jacob Keller wrote: > Dear Crystallographers, > > I am looking for references which discuss the validity of the > assertion that multiple crystal structures of the same or similar > proteins can be considered freeze-frame snapshots of actual > conformations assumed in solution. In a way, the assertion seems > almost definitely true to me, but on the other hand, I could imagine > some objections as well. Seems there should be some classic literature > here... > > All the best, > > Jacob > > > > -- > ******************************************* > Jacob Pearson Keller > Northwestern University > Medical Scientist Training Program > email: [email protected] > *******************************************
