Dear colleagues,
We are pleased to announce the release of OASIS version 4.2 and the
pipeline IPCAS (Iterative Protein Crystal-structure Automatic Solution)
version 1.0, which combines OASIS with other protein crystallographic
programs to perform automatic iterative direct-method phasing, density
modification and model building/refinement. IPCAS1.0 is capable of
performing the following tasks leading to a model amount to more than 90%
of the whole structure in favorable cases:
* SAD phasing at low Bijvoet ratio (< 1%), low redundancy (< 4) and/or
low resolution (below 3Å)
* Difficult SIR (or SAD) phasing with the aid of known phases at the
resolution of ~8Å
* MR-model completion based on a starting model corresponding to ~20%
of the whole structure
* Completion of structure models from different sources other than MR
* Structure solution by extension of known phases at the resolution
below 4Å
OASIS4.2 and IPCAS1.0 are CCP4i compatible and are freely available at
http://cryst.iphy.ac.cn for academic users.
People who already have the IPCAS package before this April, please update
to the present release, which includes some improvements and bugs fixing.
Hai-fu Fan
__________________________
Institute of Physics
Chinese Academy of Sciences
Beijing 100190
P. R. China
