On Wed, 2012-05-23 at 18:06 +0300, Nicholas M Glykos wrote:
> This is an amplitude modification. It does not change the fact that
> the
> sigmas are not being used in the inversion procedure
Nicholas,
I am not sure I understand this - perhaps we are talking about different
things. Even if by inversion procedure you mean simple calculation of
(2fo-fc)*exp(i*phi), the fc is still technically a product of the
refinement, which unless based on trivial least square target (i.e. no
weights) does factor in experimental errors. The (2mFo-DFc) map is even
more obviously dependent on the errors. Again, I believe that the
differences will be minor, but if one calculates a map with refmac
either with or without factoring in experimental errors, there will be
*some difference*. Thus, the experimental errors will affect the
resulting map. Could you please clarify?
Cheers,
Ed
--
Oh, suddenly throwing a giraffe into a volcano to make water is crazy?
Julian, King of Lemurs
