Rex,
\begin{shameless self-advertizing}
Once upon a time we did a systematic study how to optimize crystal size. The
study was done with knowledge of the protein solubility (which is not normally
available, of course) and we showed that you can still do it when you do not
have this information.
Perhaps worth reading. The paper does not end with a shocking conclusion, but
more or less with "if you do a systematic study, you can improve crystal
volume".
http://www.springerlink.com/content/16133650m43x013g/?MUD=MP
\end{shamelss self-advertizing}
Mark
-----Original Message-----
From: REX PALMER <[email protected]>
To: CCP4BB <[email protected]>
Sent: Wed, Jul 4, 2012 3:55 am
Subject: [ccp4bb] getting larger protein crystals
Does anyone have any new tips/methods for improving crystal size once the
initial conditions have been established?
Rex Palmer
http://www.bbk.ac.uk/biology/our-staff/emeritus-staff
http://rexpalmer2010.homestead.com
