Title/Position: Associate Scientist, Biochemistry Summary ARIAD Pharmaceuticals Inc. is seeking an independent and highly motivated associate scientist with a strong background in protein biochemistry, molecular biology and tissue culture to join our small molecule oncology drug discovery team. The successful candidate will play an important role in expanding ARIAD’s capability and platform in structural chemistry and structure-based drug design and will join an interdisciplinary research group encompassing biophysical chemistry, structural chemistry (X-ray and NMR), computational chemistry and cheminformatics to support our internal drug discovery efforts. Duties and Responsibilities
Design and make protein expression constructs in various protein expressing systems Purify protein in sufficient quantities for structural and biophysical studies Grow baculovirus/insect cells for protein expression and production Set up protein crystallization experiments Experience and Requirement B. S. or master degree in life science related fields At least two years of lab experience Experience in cellular culture of bacteria, insect or mammalian cells Experience in molecular cloning Experience in protein purification and characterization (chromatography purification on AKTA systems and protein analysis by western blot, SDS and native gel electrophoresis) Experience in protein crystallization or enzymology would be a plus Good communication and teamwork skills Applications Catherine Freni: [email protected] or Xiaotian Zhu: [email protected]
