Post-doctoral positions are available in the Netherlands Cancer Institute in the groups of Anastassis (Tassos) Perrakis and Titia Sixma (http://xtal.nki.nl). The Netherlands Cancer Institute (http://www.nki.nl) is a center of excellence with a high standard of biological research and an interactive international atmosphere. It is located in Amsterdam, with all its cultural amenities, close to the Schiphol airport. The groups are closely associated and have an interest in structural studies coupled to functional analysis, combined with activities in method development for structural biology. Our department also hosts the "Protein Facility" with equipment that includes high throughput crystallization and crystal visualization robotics, an X-ray facility, Biacore surface plasmon resonance, isothermal titration calorimetry (ITC), static light scattering (MALLS), versatile systems for fluorescence based equilibrium and transient state kinetics analysis (a versatile plate reader and stopped-flow), an Orbitrap mass spec, and operational facilities for E.coli, insect cells and mammalian cells based protein expression. The project in the laboratory of Titia Sixma is focused at the interface of ubiquitin (de)conjugation and DNA repair. The projects in Tassos Perrakis group are about Autotaxin and/or proteins that regulate mitotic progression. We are looking for enthusiastic researchers with experience in molecular biology and/or biochemistry and/or protein crystallography. Applicants should write an e-mail with CV and names of three references to t.si...@nki.nl or a.perra...@nki.nl
Tassos & Titia
