Dear Chang,

    Some CCP4 progs can be used with a multi-core machine,  
using OpenMP threads (including refmac it would appear). You will 
need to compile the code from source rather than taking the binary 
versions, which is much less convenient. 
    Even if the CCP4 apps are not parallel themselves, they can access
a parallel version of libraries e.g. FFTW, LAPACK. Again you will 
probably need to compile CCP4 from source and link with the correct 
libraries. 
    The third option (as Tim described) is task-farming. Bioinformations 
typically use our HPC in this way. 
     Given that you do not want to overtax your machine you might set
OMP_THREAD_NUM=2 which would give you less than 2x speedup,
I am not sure it is worth the hassle.

Adam


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