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Dear Wei,

if you are not restricted to 2 ligands, you can also look at human
serum albumin, http://pdb.org/pdb/101/motm.do?momID=37

Best regards,
Tim

On 03/04/2014 04:48 AM, Wei Shi wrote:
> Dear all, Does anyone happen to know examples of 2 ligands bind to
> a single protein / each monomer protein in 2 different ligand
> binding pockets? I know the following example: (1).
> phosphofructokinase, which binds ATP as both a ligand and a
> feedback inhibitor in different sites (2).  2 cAMP bound to each E.
> coli CAP monomer in the crystal structure.
> 
> Does any of you know other examples? Thank you so much!
> 
> Best, Wei
> 

- -- 
- --
Dr Tim Gruene
Institut fuer anorganische Chemie
Tammannstr. 4
D-37077 Goettingen

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