Hi SDY,

It would be unlikely unless you have other reasons to believe it (biology,
surrounding environment), but that blob looks a little like a possible
phospho-histidine. It might be worth a looking into?

That said, buffer or metals are probably the more likely explanation.

Shane Caldwell
McGill University


On Sat, Mar 8, 2014 at 12:28 AM, SD Y <[email protected]> wrote:

> Hi,
>
> During refinement, I see a strong density next to His and I have tried
> metal ions  and water but it seems to be different.  Known components of
> crystallization are Tris, NaCl, BME, MgOAc, PEG3350. Its only seen in one
> chain of AU. Are there any suggestions?
>
> Thanks in advance
> SDY
>

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