Rotate chi2 bond (CB-CG) and have two alternative conformations for the His.
Add two water molecules (50% occupancy) each making a H-bond with the NE2
atoms (alternative  1 and 2)  of the His.

 

George

 

 

From: CCP4 bulletin board [mailto:[email protected]] On Behalf Of SD Y
Sent: Saturday, March 08, 2014 7:29 AM
To: [email protected]
Subject: [ccp4bb] density near Histidine

 

Hi,

 

During refinement, I see a strong density next to His and I have tried metal
ions  and water but it seems to be different.  Known components of
crystallization are Tris, NaCl, BME, MgOAc, PEG3350. Its only seen in one
chain of AU. Are there any suggestions?

 

Thanks in advance

SDY

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