Hi Natalie
Try -
P. Román, C. Guzmán-Miralles and A. Luque,
Acta Cryst. (1993). B49, 383-386 [ doi:10.1107/S0108768192007201 ]
"Estimate of a relationship between the number of atoms and the
volumes of the unit cells of organic compounds"
& references therein
On 5 May 2014, at 12:07, Natalie Tatum wrote:
Hi all,
I've had an interesting question from an undergradute student,
asking if there's any specific reference for the "18Å rule of thumb"
in small molecule crystallography for dividing the volume of a unit
cell by 18 for the approximate number of non-hydrogen atoms.
I'm afraid my google-fu has failed me, but I was curious as to
whether there is a reference associated with the practice of if it's
just one of those handy little pieces of advice for crystal screening.
Thanks,
Natalie
Natalie J. Tatum
http://about.me/tatum.nj
PhD Researcher
Pohl Group
Durham University
Harry
--
** note change of address **
Dr Harry Powell, MRC Laboratory of Molecular Biology, Francis Crick
Avenue, Cambridge Biomedical Campus, Cambridge, CB2 0QH
