Thanks all for the links, everyone. A couple of interesting reads. Hi Natalie
Try - P. Román, C. Guzmán-Miralles and A. Luque, Acta Cryst. (1993). B49, 383-386 [ doi:10.1107/S0108768192007201 ] "Estimate of a relationship between the number of atoms and the volumes of the unit cells of organic compounds" & references therein On 5 May 2014, at 12:07, Natalie Tatum wrote: Hi all, > > I've had an interesting question from an undergradute student, asking if > there's any specific reference for the "18Å rule of thumb" in small > molecule crystallography for dividing the volume of a unit cell by 18 for > the approximate number of non-hydrogen atoms. > > I'm afraid my google-fu has failed me, but I was curious as to whether > there is a reference associated with the practice of if it's just one of > those handy little pieces of advice for crystal screening. > > Thanks, > > Natalie > > Natalie J. Tatum > http://about.me/tatum.nj > PhD Researcher > Pohl Group > Durham University > > Harry -- ** note change of address ** Dr Harry Powell, MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge, CB2 0QH
