Dear all

I am working with a membrane protein without known structure. The closest 
protein in PDB has 10% sequence identity/25% similarity to my protein.

What is the best method and software to do homology modeling while I try to get 
the crystal? Is the ligand binding site prediction reliable? There is no 
available experimental data on this protein except to sugest it is some type of 
ion transport.

Thank you.

Theresa

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