A postdoctoral position is available immediately on structural studies of
protein-protein interactions at the core of the human Hedgehog signaling
pathway, as part of a long-term collaboration between the laboratories of Rune
Toftgård and Luca Jovine at the Department of Biosciences and Nutrition &
Center for Innovative Medicine at Karolinska Institutet.
The Department of Biosciences and Nutrition has state-of-the-art equipment for
protein expression in E. coli, insect and mammalian cells, purification,
crystallization and in house X-ray diffraction data collection (including
Mosquito robotics and a brand new Rigaku CompactHome Lab system with a Pilatus
P200K detector). Frequent access to synchrotron sites and excellent
computational facilities are also available. With their close integration of
academic, clinical and industrial research, KI and the Center for Innovative
Medicine offer a highly international and collaborative environment for
biomedical studies.
To qualify, applicants must hold a Ph.D. or a foreign qualification deemed
equivalent to a doctoral degree. The candidate must have significant experience
in studying protein-protein interactions using both biochemical and
crystallographic approaches. Previous experience with protein expression in
mammalian cells will be a distinct advantage. Familiarity with SAXS data
collection and processing will also be a plus. At least one first author paper
in a high quality international peer-reviewed journal, fluency in english and a
strong personal drive to excel in science are required.
For additional information and to apply please visit the Karolinska Institutet
NetRecruiter system (deadline 29 June):
https://ki.mynetworkglobal.com/en/what:job/jobID:38811/where:4/
Further information may also be found here:
http://ki.se/people/rutoft
http://jovinelab.org
Cherry et al. Acta Cryst. D 69:2563-2579 (2013)
http://www.ncbi.nlm.nih.gov/pubmed/24311597
Teglund & Toftgard Biochim. Biophys. Acta 1805:181-208 (2010)
http://www.ncbi.nlm.nih.gov/pubmed/20085802
With best regards,
Luca Jovine & Rune Toftgård
----------------------------------------------------------------
Luca Jovine, Ph.D.
Professor of Structural Biology & EMBO Young Investigator
Karolinska Institutet
Department of Biosciences and Nutrition & Center for Biosciences
Halsovagen 7, SE-141 83 Huddinge, Sweden
Voice: +46.(0)8.524-81136 FAX: +46.(0)8.6081-501
E-mail: [email protected]
W3: http://jovinelab.org
----------------------------------------------------------------
