You can take XDS data into Pointless & Aimless (the CCP4 Data Reduction task) either from the unscaled INTEGRATE.HKL or the scaled XDS_ASCII.HKL file (or files). In the case of a single XDS_ASCII.HKL you don't need to rescale it in Aimless, though you can if you want.
Aimless uses a similar but not identical scaling model to XDS, which may be better or worse (and how do you judge?). Phil On 11 Nov 2014, at 19:50, wtempel <[email protected]> wrote: > Hello all, > in a discussion on this board, Kay Diederichs questioned the effect of > scaling data in AIMLESS after prior scaling in XDS (CORRECT). I understand > that the available alternatives in this work flow are to specify the AIMLESS > ‘onlymerge’ command, or not. > Are there any arguments for the preference of one alternative over the other? > Thank you for your insights, > Wolfram Tempel >
