Thanks for all the replies and sorry for rerun of a thread. I however have two additional questions: - Why is the pdb still available without any obvious sign of the fraud? - Why is the paper stil available ?
Fred ----- Frédéric Kerff Chercheur qualifié F.R.S.-FNRS Cristallographie des protéines Centre d'Ingénierie des Protéines Université de Liège 17, Allée du 6 Août - Bat B5a 4000 Liège (Belgium) Tel.: +32 (0)4 3663620 Fax: +32 (0)4 3663772 > Le 6 févr. 2015 à 12:16, Randy Read <[email protected]> a écrit : > > Actually, if you go back through the archive of CCP4-BB from the first time > this came up, I think you'll find that there are real crystals with apparent > gaps in the packing. This can arise because of statistical disorder, where > there are two or more ways that a statistically-disordered layer in the > crystal can mediate the interaction between ordered layers. So not finding a > connected packing is something to look closely at and worry about, but it > doesn't necessarily indicate that somebody did a bad job of making up a > structure. > > Randy > > On 6 Feb 2015, at 11:09, Robbie Joosten <[email protected] > <mailto:[email protected]>> wrote: > >> Not in real crystal structures ;) >> >> Cheers, >> Robbie >> >> Sent with my Windows Phone >> Van: Kerff Fred <mailto:[email protected]> >> Verzonden: 6-2-2015 12:02 >> Aan: [email protected] <mailto:[email protected]> >> Onderwerp: [ccp4bb] Absence of contact between layers in a crystal >> >> Hello, >> >> Looking at structure 2HR0 ("The structure of complement C3b provides >> insights into complement activation and regulation. »,Abdul Ajees, A., >> Gunasekaran, K., Volanakis, J.E., Narayana, S.V., Kotwal, G.J., Krishna >> Murthy, H.M.; (2006) Nature 444: 221-225), I noticed the absence of >> contacts between layers in the crystal. Is it something that has already >> been observed in other crystals? >> >> Best regards, >> >> Fred >> ----- >> Frédéric Kerff >> Chercheur qualifié F.R.S.-FNRS >> Cristallographie des protéines >> Centre d'Ingénierie des Protéines >> Université de Liège >> 17, Allée du 6 Août - Bat B5a >> 4000 Liège (Belgium) >> Tel.: +32 (0)4 3663620 >> Fax: +32 (0)4 3663772 >> >> >> >> > Le 6 févr. 2015 à 10:12, Tim Gruene <[email protected] >> > <mailto:[email protected]>> a écrit : >> > >> > -----BEGIN PGP SIGNED MESSAGE----- >> > Hash: SHA1 >> > >> > Dear Smith, >> > >> > The sca file most likely does not contain flags. pointless can read >> > the sca file, standardise it to ccp4 standards and freerflag marks >> > random reflections. You should use the maximum of 500 unique >> > reflections or 5% of the unique reflections, whichever is larger. >> > >> > Best, >> > Tim >> > >> > On 02/06/2015 09:49 AM, Smith Lee wrote: >> >> Dear All, I have a sca file. Will you please tell me by which >> >> software or how I can know whether the sca file contains R-free >> >> tags? If not, by which software or how I can add the R-free tags? >> >> And how much of the reflections I add the R-free tags? I am looking >> >> forward to getting your reply. Smith >> >> >> > >> > - -- >> > - -- >> > Dr Tim Gruene >> > Institut fuer anorganische Chemie >> > Tammannstr. 4 >> > D-37077 Goettingen >> > >> > GPG Key ID = A46BEE1A >> > >> > -----BEGIN PGP SIGNATURE----- >> > Version: GnuPG v1.4.12 (GNU/Linux) >> > >> > iD8DBQFU1IWVUxlJ7aRr7hoRAmZHAJ4+6wREnwkFN0EhfErAA0tPSopKKwCgiLdi >> > j0JFZac4kAh8twpov71MG84= >> > =XN57 >> > -----END PGP SIGNATURE----- > > ------ > Randy J. Read > Department of Haematology, University of Cambridge > Cambridge Institute for Medical Research Tel: + 44 1223 336500 > Wellcome Trust/MRC Building Fax: + 44 1223 336827 > Hills Road E-mail: [email protected] > <mailto:[email protected]> > Cambridge CB2 0XY, U.K. www-structmed.cimr.cam.ac.uk >
