Hi Jürgen,

sorry - that's what I get when mailing while boarding ... No, I'd just collect 
360 degrees, and if the crystal is still ok, another 360, ... This way one 
- obtains high completeness and multiplicity
- can discard frames with "too much" radiation damage
- does not have to worry about the starting point of data collection.
To make the most of the second 360°, you should change some parameter: 
wavelength, rotation axis (requires a BL with kappa or Prigo), or at least 
distance (by few percent).

When I read that 1° frames are collected, I just wonder why? Because it used to 
be done like that in the good old times?

HTH,

Kay

On Fri, 17 Apr 2015 11:55:42 +0000, Jurgen Bosch <[email protected]> wrote:

>Just to clarify, I think what Kay meant with "strategy" is that you don't just 
>shoot at the crystal and collect. You should figure out what is the optimum 
>start and end point of your data collection. Best to be cautious and not 
>immediately go for highest resolution and not fry your crystal. A 4 A complete 
>anomalous data set is better than a partial 3.2A one.
>J?rgen
>
>
>......................
>J?rgen Bosch
>Johns Hopkins University
>Bloomberg School of Public Health
>Department of Biochemistry & Molecular Biology
>Johns Hopkins Malaria Research Institute
>615 North Wolfe Street<x-apple-data-detectors://4>, W8708
>Baltimore, MD 21205<x-apple-data-detectors://5/0>
>Office: +1-410-614-4742<tel:%2B1-410-614-4742>
>Lab:      +1-410-614-4894<tel:%2B1-410-614-4894>
>Fax:      +1-410-955-2926<tel:%2B1-410-955-2926>
>http://lupo.jhsph.edu<http://lupo.jhsph.edu/>
>
>On Apr 17, 2015, at 06:37, Kay Diederichs 
><[email protected]<mailto:[email protected]>> wrote:
>
>Hi,
>I'd say using a Pilatus detector in fine-slicing mode and lowdose/high 
>multiplicity will give you better chances to solve the structure. The right 
>strategy makes a difference ...
>Best,
>Kay
>

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