Dear All,

We are looking for two associate scientists in protein 
biochemistry/crystallography to join our structural biology group at Amgen 
(Cambridge, Massachusetts).  Please see the following description of the job 
and apply at 
http://careers.amgen.com/en/jobs/descriptions/associate-scientist-protein-biochemistrycrystallography-cambridge-job-5550466.
  Best ragards, Xin  Associate Scientist - Protein 
Biochemistry/CrystallographyAuto Req #: 32607BR
Career Categories:  Research
Location:  US - MA - Cambridge
 Amgen Job Description 

|  Amgen is a leading global biotechnology company, with a mission to serve 
patients around the world. As a science-based, patient-focused organization, we 
discover and develop innovative therapies to treat serious illnesses. Our 
medicines have made a dramatic difference in the lives of millions. To underpin 
our commitment to serve patients, Amgen is significantly expanding our Research 
and Development facility in Cambridge MA (AMA).

We are looking for a highly motivated and talented protein biochemist or 
crystallographer to join the AMA Structural Biology group. This laboratory 
provides comprehensive molecular insight and structure-based design for drug 
target assessment, mechanism of action, protein-protein and protein-ligand 
interactions, as well as protein engineering to facilitate drug discovery 
across various important therapeutic areas. The successful candidate will have 
the opportunity to contribute directly to the exciting drug discovery process 
through structural studies on a wide variety of important biological systems, 
especially human integral membrane proteins.

The candidate will be part of a structural biology group with responsibilities 
including (but not limited to) the purification of target proteins for x-ray 
crystallographic studies. The successful candidate will work in teams to 
develop, implement, and perform protein purification protocols. He/she will 
work closely with molecular biologists and protein biochemists in the protein 
technology group and should demonstrate excellent verbal and written 
communication skills. Additional responsibilities include maintaining 
laboratory notebooks, participating in group and project meetings and, as 
needed, presenting to groups and aiding in the writing of papers and patent 
applications.  |


 Basic Qualifications 

|  - Master’s degree & 2 years of Scientific experience
OR 
- Bachelor’s degree & 4 years of Scientific experience  |


Preferred Qualifications 

|  - Bachelor’s degree in protein biochemistry or related discipline with 4 
years of protein purification lab experience (academic and/or industrial) 
OR Master’s degree in protein biochemistry or related discipline with 2 years 
of protein purification lab experience (academic and/or industrial) 
- Knowledge of state-of-the-art protein biochemistry techniques and hands on 
experience purifying proteins using affinity chromatography, ion exchange 
chromatography, and size exclusion chromatography.
- Experience with AKTA chromatography hardware and software.
- Excellent communication skills (both written and oral) and the ability to 
work well in teams
- Experience in protein biophysical characterization is a plus
- Experience in protein crystallography is a plus
- Experience in the purification of membrane proteins is a plus  |

Amgen is an Equal Opportunity/Affirmative Action employer and will consider all 
qualified applicants for employment without regard to race, color, religion, 
sex, national origin, protected veteran status, or disability status.



  

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