Are you sure there really are 4 chains?  50% solvent may be average, but we've 
had crystals with closer to 80%.


________________________________
From: CCP4 bulletin board [CCP4BB@JISCMAIL.AC.UK] on behalf of Pooja Kesari 
[pkesar...@gmail.com]
Sent: Tuesday, January 24, 2017 10:42 PM
To: CCP4BB@JISCMAIL.AC.UK
Subject: [ccp4bb] Bad density for chains

Dear All,

I have a 2.6 A resolution structure having four chains in an asymmetric unit.
The chain A and B have density for almost all residues however we don't have 
proper residue density in chain C and D.What can be tried to build chain C and 
D ?



Many Thanks
Pooja

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