We invite applications for a PhD position and a postdoc position in
the research group of Dr. Sonja Lorenz at the Rudolf Virchow Center
for Experimental Biomedicine, Würzburg, Germany.
The Lorenz lab explores the catalytic and regulatory mechanisms of
ubiquitin ligases and their functions in cancer signalling (see eLife
2017;6:e21036). We combine X-ray crystallography with biophysical,
biochemical, and cell biological analyses. Depending on individual
qualifications and interests, the successful applicants will have the
opportunity to gain experience in various aspects of this
The Rudolf Virchow Center is a highly competitive international
research institute with outstanding technical infrastructure. The
Lorenz lab has access to state-of-the-art instrumentation in X-ray
crystallography, high-field NMR, cryo-EM, and an extensive range of
modern biophysical and cell biological equipment. We are integrated
into a stimulating research environment that includes the Biocenter,
the Research Center for Infectious Diseases, and the university
hospital in Würzburg, and we maintain several active international
PhD applicants should have a M.Sc. degree in molecular biology,
biochemistry or a related discipline and a strong interest in
enzymatic mechanisms and structure-function studies on proteins.
Experience in protein biochemistry is desirable.
Postdoc applicants should have strong expertise in protein X-ray
crystallography, protein biochemistry, and biophysics. Experience with
mammalian or baculovirus expression systems is beneficial.
English language skills are essential; knowledge of German is not required.
The successful PhD applicant will have the opportunity to enroll in
the ‘Graduate School of Life Sciences’ in Würzburg – a prestigious
international PhD program funded by the German Excellence Initiative.
He/she will also be affiliated with the new DFG-funded Graduate
Training Group “Understanding Ubiquitylation: from molecular
mechanisms to disease” (http://www.uni-wuerzburg.de/grk2243/home/).
Both positions can start immediately or upon mutual agreement. Salary
will be according to the German TVL scale. In case of equivalent
qualifications, disabled applicants will be preferentially considered.
Würzburg is located in a beautiful, wine-growing area in proximity to
Frankfurt (1 hour by train) and Munich (2 hours by train).
Applications should be sent to Sonja Lorenz by email
(sonja.lor...@virchow.uni-wuerzburg.de) and are expected to include a
letter of motivation detailing research interests and expertise, a CV,
and the contact information for at least two references. Review of
applications will begin immediately.
Sonja Lorenz, PhD
Rudolf Virchow Center for Experimental Biomedicine
Josef-Schneider-Strasse 2, Haus D15
97080 Würzburg, Germany