Is there a straight-forward way to estimate the amount of missing electron density that a particular protein structure is missing based on the difference between Fo and Fc?
It appears that the normalization of the Fc due to the employing of a maximum entropy method that keeps Fo and Fc comparable to the standard deviation of Fo would make this difficult. Or am I missing something? Cheers, Hunter -- Hunter Moseley, Ph.D. -- Univ. of Kentucky Associate Professor, Dept. of Molec. & Cell. Biochemistry / Markey Cancer Center / Resource Center for Stable Isotope Resolved Metabolomics Not just a scientist, but a fencer as well. My foil is sharp, but my mind sharper still. --------------------------------------------------------------- Email: [email protected] (work) [email protected] (personal) Phone: 859-218-2964 (office) 859-218-2965 (lab) 859-257-7715 (fax) Web: http://bioinformatics.cesb.uky.edu/ Address: CC434 Roach Building, 800 Rose Street, Lexington, KY 40536-0093
