Not much idea.

I tend to build small amounts at the termini of your current model using
the better model as a guide then re-refine and hope you can keep going..
Eleanor

On 2 October 2017 at 15:42, Vikram Dalal <[email protected]> wrote:

> Hi all,
>
>
> I am solving a protein data of 2.6 A. It has two monomers in ASU. It has
> 377 residues. I have built residues 26 to 36 and 41 to 377 in A chain while
> B chain has model 42 to 129, 146 to 168 and 189 to 371. Current R factor
> and R Free is 23.2  and 28.5, respectively. I have attached electron
> density (fourier map at 1.0 contour and difference map at 2.5) figures for
> 130 to 145, 169 to 188 and C terminal region of B chain and superposed
> model of A chain is shown in green color.
>
> I have tried manually building missing residues of B chain according to A
> chain model, but R free increased to 29.
>
> Any suggestions will be highly aprreciated.
>
>
> Thanks & Regards,
>
>
>
>
>

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