Good morning, We have two relevant job postingings that I would like to share.
Thank you for your attention :) Artem https://careers.massbio.org/job/sr-scientistprincipal-scientist-computational-chemistry/49455467/ and https://careers.massbio.org/job/scientist-enzymology-protein-chemistry/49690257/ Sr Scientist/Principal Scientist - Computational Chemistry Enko discovers and develops sustainable solutions for farmers to protect their crops from pests and disease. It’s proprietary discovery platform represents a revolutionary approach to rapidly discover novel, safe and economical solutions that are needed to ensure efficient food production. Led by a team of proven scientists, entrepreneurs and ag-industry veterans, Enko uses innovative science and agile design principles to rapidly develop field-ready crop protection solutions that overcome the rising resistance barriers traditional pesticides face. Enko team members will be entitled to participate in Health, Dental, Vision, Life and Disability insurance, 401(k) plan, and other similar fringe benefit plans as may be provided by the Company. We are looking to add a Computational Chemist to join the Chemistry team. This person will enable the discovery of small molecules for the modulation of novel biological targets for use in the control of agriculturally important weeds and pests. Major responsibilities will include: Build the computational chemistry project strategy to enhance the advancement of targets from DNA-encoded library hits to candidate compound selection Build the requisite infrastructure to conduct this research, including identifying tools and technologies needed to support and accelerate pipeline development and champion their acquisition or the establishment of collaborations Lead the structure-based drug design (SBDD) efforts utilizing the suite of computational chemistry tools including docking/scoring, molecular dynamics simulations, homology modeling, watermap, and FEP+ Collaborate with medicinal chemists and biologists to create a rich and diverse pipeline that will address the company’s goals The ideal candidate will have demonstrated an ability to apply their expertise in computational chemistry to advance multiple, small molecule discovery campaigns from screening to development candidates. They will have demonstrated the ability to thrive in a dynamic, fast-paced, innovative environment. Excellent written and oral communication skills are required, as is the desire and ability to excel in a multidisciplinary environment both as a leader and member across multiple project teams. As an early addition to the scientific team, this person will have an opportunity to help us establish a culture that nurtures scientific excellence, a sense of urgency to achieve project success, and success built on collaboration and personal accountability. Qualifications and Skills D. in Chemistry or a related discipline with 3-5 years of experience in application of computational chemistry to drug or crop protection chemistry discovery Demonstrated expertise in all aspects of modern computational chemistry including receptor- and structure-based design, conformational analysis, molecular dynamics, QSAR, binding free energy calculations and cheminformatics Track record of accomplishment in small molecule discovery and/or molecular modelling fields Demonstration of project leadership and data-driven decision making Excellent written and oral communication Strong background in medicinal chemistry, biology, statistics and computer programming is a plus No Employment Agencies please, the Company is not responsible for any fees related to candidates that are unsolicited. Job Code – PGP13 (Use Job Code in subject line of all communications) Company: Enko Chem Contact Name: John Gilroy Email: [email protected] Position Location: Boston, MA Minimum Required Education: Doctorate Minimum Years’ Experience: 3-5 years Scientist, Enzymology & Protein Chemistry Enko discovers and develops sustainable solutions for farmers to protect their crops from pests and disease. It’s proprietary discovery platform represents a revolutionary approach to rapidly discover novel, safe and economical solutions that are needed to ensure efficient food production. Led by a team of proven scientists, entrepreneurs and ag-industry veterans, Enko uses innovative science and agile design principles to rapidly develop field-ready crop protection solutions that overcome the rising resistance barriers traditional pesticides face. Enko team members will be entitled to participate in Health, Dental, Vision, Life and Disability Insurance, 401(k) Plan and other similar fringe benefit plans. We are looking for a creative and highly skilled protein chemist/enzymologist to join our multidisciplinary team. This scientist will be responsible for designing, validating, and conducting enzymatic/biochemical assays and for supporting the overall activities of the team which may include: molecular biology, protein expression and purification, cell culture, and other related activities. Major responsibilities will include: Assay development, validation, execution, and data analysis in support of target-based lead optimization programs Design and independent execution of molecular biology and protein chemistry experiments (e.g. molecular cloning, expression, purification) Experimental data record-keeping and analysis in the context of corporate databases and pipelines Effectively managing multiple project flows Team communication in a matrixed environment The ideal candidate will have demonstrated an ability to apply their expertise in conducting enzyme assays in microplate format, will have strong data analysis and interpretation skills, and exhibit stringent attention to detail, and excellent notebook and record-keeping practices. They will effectively work in a team environment, communicating and planning research with other teammates and departments. Qualification and Skills: Biochemical assay expertise Independent thinking and trouble-shooting abilities General laboratory practical expertise (biochemistry, enzymology, protein chemistry) Protein purification/characterization and/or eukaryotic cell culture Experience with automated/robotic assay technologies, liquid handler programming Robust experience with DNA cloning and bacterial culture Excellent oral and written communication skills PhD in Biochemistry or related field with 3+ years relevant experience or M.Sc. in a relevant field with 5+ years of relevant experience No Employment Agencies please, the Company is not responsible for any fees related to candidates that are unsolicited. Job Code – AEP15 (Use Job Code in subject line of all communications) Company: Enko Chem Contact Name: John Gilroy Email: [email protected] Position Location: Boston, MA Minimum Required Education: Masters Minimum Years’ Experience: 3-5 years ######################################################################## To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/webadmin?SUBED1=CCP4BB&A=1
