Hello, it would be useful to see how the merging of the normal data looks in 
addition to the anomalous, which could be a bit better, I fear. Are you 
expecting significant anomalous differences e.g. Se-Met, S with long 
wavelength, H-atom, etc? You should have quite high redundancy with all that 
data even with monoclinic. HTH a bit. Jon Cooper

Sent from ProtonMail mobile

-------- Original Message --------
On 4 Nov 2020, 16:30, Almudena Ponce Salvatierra wrote:

> Hello everyone,
>
> I have collected 6 small datasets from a crystal, each from a different point 
> on the crystal to avoid radiation damage, and there is some overlap among 
> them, as follows:
>
> - dts1: 0-90 degrees
> - dts2: 60-150 degrees
> - dts3: 120-210 degrees
> - dts4: 180-270 degrees
> - dts5: 240-330 degrees
> - dts6: 300-390 degrees
>
> Diffraction is very poor and, after processing, I've cut resolution at around 
> 5 Angstroms for all of them. The space group is C2. Feeding the 6 of them to 
> scale_and_merge in Phenix gives the attached output. Does anybody who has 
> merged such low-resolution anomalous data before know whether this is a 
> "good" indicator (meaning there's a tiny light at the end of the tunnel) or 
> rather not?
>
> Any suggestions? (besides the obvious "go back to the lab and grow new 
> crystals")
>
> My aim is to combine these phases with a partial molecular replacement 
> solution and a native dataset at 3.5 Angstroms. Hopefully, then I would be 
> able to finish building the model.
>
> Thanks a tone in advance!
>
> Best,
>
> Almudena
>
> ---------------------------------------------------------------
>
> To unsubscribe from the CCP4BB list, click the following link:
> https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1

########################################################################

To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

Reply via email to