Dear Afshan,

It is not totally clear to me how you did the merging, however, I have good 
experiences with that particular residue KCX in refinement. I used the Replace 
residue functionality of COOT described here: 
https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/web/docs/coot.html#Mutating-to-a-Non_002dStandard-Residue


Kind regards,

Bjarte Aarmo Lund
Postdoc
UiT The Arctic University of Norway

From: CCP4 bulletin board <[email protected]> On Behalf Of Afshan Begum
Sent: Monday, February 8, 2021 14:46
To: [email protected]
Subject: [ccp4bb] Fixing Modified residue

Dear Expert,

I have a trouble to fix the lysin modified residue in to the PDB coordinate.
what i did,
I get the KCX(Modified lysin) coordinate from monomer library in COOT (0.9) , 
merge in to the coordinate file , its listed into position 193 lysin then  run 
rafmac 5 , its place the residue but as unconnected and produce its own number.
In the second step
I take the kcx coordinate in the text pdb file and place into between 192 and 
194 and change reside number 193 . Save it.
Now it can not be read for further refinement.
Could you people suggest me how to fix it?
Would be highly thankful to you.


Best Regards
===============================
 Afshan


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