*Postdoc in Structure-Based Ligand Discovery*

We are recruiting for a post-doctoral position in structure-based ligand
discovery in the Shoichet lab at the University of California San Francisco
(UCSF) (https://bkslab.org/) (https://bkslab.org/people/current_members). We
are particularly interested in recruiting investigators with protein
biochemistry and crystallography backgrounds interested in training in
structure-based drug discovery.


Research focuses on developing and testing new ligand discovery methods,
with a GPCR focus.  Open projects include structure-based discovery of new
analgesics, GPCR deorphanization, antiviral discovery against SARS-2, and
particularly biophysical testing of new docking methods in experimental
model systems. Recent papers include:


Tummino et al., *Science *2021
<https://science.sciencemag.org/content/early/2021/06/22/science.abi4708/tab-article-info>

Schuller et al., *Science Adv* 2021
<https://advances.sciencemag.org/content/7/16/eabf8711>

Pottel et al., *Science* 2020
<https://science.sciencemag.org/content/369/6502/403.long>

Stein et al., *Nature *2020
<https://www.nature.com/articles/s41586-020-2027-0>

Lyu et al., *Nature* 2019
<https://www.nature.com/articles/s41586-019-0917-9>



Top facilities are available in a friendly, collaborative environment, and
the lab is well-resourced.  Stipend and benefits at or above NRSA levels.
If interested please send a cover letter, CV and contact information for
three referees to Brian Shoichet ([email protected]).   Deadline Aug
15, 2021.


-- 
Brian Shoichet, Professor, UCSF
latest science from the lab:  *http://www.bkslab.org/
<http://www.bkslab.org/contact.php>*

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