Dear colleagues,

The Hochberg group in Marburg is looking for a self-motivated postdoc to study 
how molecular machines become more efficient and complex through evolutionary 
history starting as soon as possible. The position is funded by a Human 
Frontiers Grant for three years to study the evolution of the epsilon 
proteobacterial flagellum as part of a collaboration that includes the Beeby 
lab (cryo-electron tomography, Imperial College, UK), the Pedaci lab (single 
cell force measurements, Montpellier, France) and the Cary lab (Metagenomics, 
New Zealand).

The Hochberg lab uses ancestral sequence reconstruction to bring ancient 
protein complexes back to life and study their properties in the lab. We use a 
broad combination of biophysical techniques to study these ancient complexes, 
but in particular mass photometry, in vitro biochemistry, and cry-electron 
microscopy.  We use this approach to answer fundamental questions about how and 
why biochemical complexity evolved in the very deep past.

The candidate would have the opportunity to develop their own evolutionary 
biochemistry research program alongside the consortium project. In particular, 
we are looking for biochemists that are interested in learning evolutionary 
methods to understand how current macromolecular machines came to be the way 
they are. A willingness to learn phylogenetics and immerse themselves in 
evolutionary thought are essential. Prior knowledge of phylogenetics is not.

Marburg is a charming ancient university town in the middle of Germany, within 
an hour of Frankfurt. Our lab is part of the Max-Planck-Institute for 
Terrestrial Microbiology, which is a world leading address for microbiology and 
synthetic biology. The Max Planck Institutes are Germany’s premier basic 
science institutions. The candidate would be joining this thriving community 
and benefit from the unique, basic science focused environment and excellent 
infrastructure at the Max-Planck-Institutes.

Interested candidates should send an email with their CV, a cover letter 
detailing their motivation and contact information for at least 2 references to 
[email protected]<mailto:[email protected]>
More information about our work can be found on or website:
https://www.mpi-marburg.mpg.de/hochberg
and a more detailed description of the project can be found here:
https://www.mpi-marburg.mpg.de/642026/Open-Positions

All the best,
Georg Hochberg


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