Dear Colleagues, A postdoctoral fellow position is available in the laboratory of Xin Liu, in the Cecil H. and Ida Green Center for Reproductive Biology Sciences at UT Southwestern Medical Center to study chromatin structure and genome regulation. The basis of genome regulation by chromatin is a long-standing mystery in biology. Research in the Liu Lab is focused on structure and function of large chromatin complexes, which dictate formation of heritable chromatin structure and impact genome function. These chromatin complexes are also frequently dysregulated in human disease, including cancers and developmental disorders. To achieve the research goal, the Liu Lab uses structural biology tools, including biochemical reconstitution (e.g. protein-protein, protein-nucleosome, or protein-non-coding RNA complexes), X-ray crystallography and cryo-EM, to reveal three-dimensional structures of chromatin complexes. In addition, in the ongoing projects the Liu Lab performs structure-based functional studies in cancer and stem cells by employing genome editing and genomics tools. Examples of recent publications from the lab include: Science 350:aac4383 (2015) (PMID: 26472914<https://pubmed.ncbi.nlm.nih.gov/26472914/>), eLife 6:e31558 (2017) (PMID: 29185984<https://pubmed.ncbi.nlm.nih.gov/29185984/>), Molecular Cell 69:840-852 (2018) (PMID: 29499137<https://pubmed.ncbi.nlm.nih.gov/29499137/>), PNAS 117:16992-17002 (2020) (PMID: 32631994<https://pubmed.ncbi.nlm.nih.gov/32631994/>), Molecular Cell 77:1265-1278 (2020) (PMID: 31959557<https://pubmed.ncbi.nlm.nih.gov/31959557/>). More information can be found here: https://profiles.utsouthwestern.edu/profile/127166/xin-liu.html.<http://www.utsouthwestern.edu/education/graduate-school/postdoctoral-scholars/> Applicants with demonstrated expertise in structural biology, biochemistry, chromatin biology, or genomics are encouraged to apply. Applicants must hold a Ph.D. and/or M.D. degree with first author publications. Interested individuals should send a CV and a list of 2-3 references to: [email protected]<mailto:[email protected]> Information on our postdoctoral training program and benefits can be found in our Postdoc Handbook<http://www.utsouthwestern.edu/edumedia/edufiles/graduate_school/postdoctoral_scholars/handbook.pdf> <http://www.utsouthwestern.edu/edumedia/edufiles/graduate_school/postdoctoral_scholars/handbook.pdf> or at http://www.utsouthwestern.edu/postdocs<http://www.utsouthwestern.edu/education/graduate-school/postdoctoral-scholars/>.<http://www.utsouthwestern.edu/education/graduate-school/postdoctoral-scholars/> Kind regards,
Xin Liu, Ph.D. W.W. Caruth, Jr. Scholar in Biomedical Research Cecil H. and Ida Green Center for Reproductive Biology Sciences UT Southwestern Medical Center 5323 Harry Hines Blvd. Dallas, TX 75390-8511 Phone: 214-648-2493 Fax: 214-648-0383 E-mail: [email protected]<mailto:[email protected]> https://profiles.utsouthwestern.edu/profile/127166/xin-liu.html ________________________________ UT Southwestern Medical Center The future of medicine, today. ######################################################################## To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1 This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list hosted by www.jiscmail.ac.uk, terms & conditions are available at https://www.jiscmail.ac.uk/policyandsecurity/
