>
> This is best illustrated by Ramachandran "outliers",
> which are perfectly supported by electron density.
>

Indeed, and 3NOQ is one of my favorite examples of that, an outlier isn't
necessarily equates to wrong! However, I think torsion angles (eg, phi/psi)
are much more flexible than covalent angles/bonds and so they can possibly
afford larger deviations compared to covalent bonds/angles.

The strain caused by any one of them will distribute itself
> over all neighbouring bond lengths and angles as well as
> over the torsion angles.
>

I wonder if there is a documented study that actually shows this happening?
Clearly this must take place one way or another, but I wonder if anyone
"measured" the effect and documented it..

Pavel

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