Hi guys

I would be a bit more optimistic about this idea… If people attend the meeting 
with the objective of building some bridges they will try.  I have been to 
meetings on a biological topic where I may have been the only structural 
biologist but it was clear why I was there and I did not feel isolated, despite 
not being able to participate in every technical discussion on methods I am not 
familiar with.

Bostjan

--
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Australian Laureate Fellow
Professor of Structural Biology
School of Chemistry and Molecular Biosciences
and Institute for Molecular Bioscience (Division of Chemistry and Structural 
Biology) and Australian Infectious Diseases Research Centre
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From: CCP4 bulletin board <[email protected]> on behalf of Nukri Sanishvili 
<[email protected]>
Reply to: Nukri Sanishvili <[email protected]>
Date: Monday, 30 January 2023 at 11:40 am
To: "[email protected]" <[email protected]>
Subject: Re: [ccp4bb] Future Diffraction Methods

Hi Pavel,
Your description of the current status is exactly correct. And that's exactly 
what I am proposing to change or, more accurately, try to change. By seeking 
out and  bringing together people who do complementary and collaborative work, 
so they can set an example for others.
This, of course, isn't meant in place of more narrowly defined topical meetings 
and conferences but to be in addition to those.
James asked the community if we had new ideas and this is a new-ish approach I 
was suggesting.
Don't get me wrong - I myself will happily continue my efforts in more narrowly 
defined meetings.
Best wishes,
Nukri

On Sun, Jan 29, 2023 at 6:44 PM Pavel Afonine 
<[email protected]<mailto:[email protected]>> wrote:
Nukri,

IMO, the idea of cross-discipline meetings is great conceptually, at least for 
reasons you pointed out, but utopical in practice. When we attend our 
field-specific meetings we meet colleagues we know, we talk to collaborators 
from the past or find new ones, we have things in common that we can talk about 
to forge something new, we meet authors of papers we were excited to read, and 
so on, and so on.
I once attended a meeting of some chemistry society, well, which is not too far 
from what we are doing, really, as interpreting atomic models is essentially 
putting your chemistry knowledge into production. And, at that meeting I felt 
like I'm alone in a dark forest.
Now, I imagine, if you bring two (or more) groups of people to your meeting 
from two different domains, well, I guess you will end up having two bubbles of 
people clustered by their field of interest.

Same disclaimer goes here as yours -- no offence to any one, just thinking out 
loud...

All the best!
Pavel

On Sun, Jan 29, 2023 at 6:09 AM Nukri Sanishvili 
<[email protected]<mailto:[email protected]>> wrote:
Hi James,
This meeting has indeed been one of the best ones by its format, content, and 
atmosphere. Many thanks to all the organizers and attendees of the past. 
Nevertheless, it is not surprising that it was cancelled, given the trends in 
structural biology research. Straightforward evolutionary pressure to adapt or 
else...

Throughout my career I was always amazed (dare I say, annoyed?) how scientists 
from different fields, or even the same field but different methods, speak 
different languages. How little they understand each other, become entrenched 
in their own methods and how much of the collaboration/cooperation 
opportunities are wasted.

IMO, having a conference on "Complementary Methods in Structural Biology" with 
the emphasis on complementarity and not on individual methods, would be a great 
benefit in the long run. Hopefully it would give good examples to young 
researchers to help them develop a collaborative mindset.

If I offended anyone, it was not intentional, I promise, and apologize in 
advance.
Best wishes to all and best of luck to all who continue the effort for the 
benefit of the whole community.
Nukri





On Fri, Dec 16, 2022 at 4:11 PM James Holton 
<[email protected]<mailto:[email protected]>> wrote:
I want to thank everyone who attended the 2022 Gordon Research
Conference and Gordon Research Seminar on Diffraction Methods in
Structural Biology, as well as all those who contributed to these great
gatherings in the past.  It was an outstanding meeting if I do say so
myself. Not just because it had been so long without in-person
interaction, not just because we had zero covid cases (which I see as no
small feat of Mind over Virus), but because of this amazing community.
It is rare in this world to have such a strong spirit of collaboration,
camaraderie and openness in undertakings as high-impact as this.
Surmounting the barriers to atomic-detail imaging of biological systems
has never been more exciting and more relevant.  I am proud to be a part
of it, and honored to have served as Chair.

It is therefore with heavy heart that I report to this community that I
was the last Chair of the Diffraction Methods GRC.

The GRC Conference Evaluation Committee
(https://www.grc.org/about/conference-evaluation-committee/) voted this
year to discontinue the Diffraction Methods GRC and GRS. This ends a
46-year tradition that I feel played a vital, and vibrant role in the
work of the people who answer questions on this BB.  The reason given
was insufficient attendance.  All other metrics, such as evaluation
surveys and demographics were very strong. I have tried to appeal, but
I'm told the vote was unanimous and final. I understand that like so
many conference organizing bodies the GRC is having to make tough
financial decisions. I must say I disagree with this one, but it was not
my decision to make.

Many of the past and elected Chairs have been gathering and discussing
how to replace the Diffraction Methods GRC/GRS going forward. Many great
ideas, advice and perspectives have been provided, but that is a select
group. I feel it is now time to open up this discussion to the broader
community of structural methods developers and practitioners. There are
some important questions to ask:

* How do we define this community?
         Yes, many of us do cryoEM too, but is that one methods meeting?
or two?
* Does this community need a new diffraction methods meeting?
         As in one meeting or zero?
* Should we merge with an existing meeting?
         It would make logistics easier, but a typical GRC has 22 hours
of in-depth presentations over 5 days.  The GRS is 7 hours over 2 days.
As Chair, I found that was not nearly enough.
* Where do you think structural methods are going?
         I think I know, but I may be biased.
* Should the name change?
         From 1976 to 2000, it was "Diffraction Methods in Molecular
Biology". The word "diffraction", BTW, comes from the Latin for
"shattering of rays", and originally used to describe the iridescence of
bird feathers. That's spectroscopy!
How about:
  "Structural Methods for the Departing of Rays"

I'm sure there are many more questions, and better suggestions.  I look
forward to enlightening discussions!  GRCs have always been about
discussion, and I hope to keep that tradition alive in this community.

-James Holton
MAD Scientist

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