Hi, everybody, hi, Nukri and Pavel ! 

I fully agree with Pavel that, if the speakers are not exceptional, if they are 
(as usually) concentrated on their specific and narrow problems, 
cross-discipline meetings make us lost quite fast, they are annoying and 
useless. Richard Feynmann had the same experience, according to his books :-) 

At such meetings, people need to have a common point. However, it may be a 
point different from the SUBJECT of the research. This may be common TOOLS. And 
this indeed may lead to new ideas and results, maybe great ones. 

There is a many-years positive experience of such meetings in Pushchino in 
80ths (both of you know this place; for other readers of this post - this was 
indeed a great place !). Closer to our community, as I remember, Paul Adams and 
John Spence organized such kind of meetings about 20 years ago in US. I guess I 
know practical results from both these groups of meetings. Some 
Crystallographic Computing Schools also try to act a little bit "around the 
tools". 

Why do not we think specifically in THIS direction (which is actually what 
Nukri said, right? and somehow not so far from the previous GRC?) ? 
This is hard but feasible. But indeed hard :-( 

Best regards to everybody, 
and many thanks to James for raising the problem ! 

Sacha Urzhumtsev 

----- Le 30 Jan 23, à 2:38, Nukri Sanishvili <[email protected]> a écrit : 

> Hi Pavel,
> Your description of the current status is exactly correct. And that's exactly
> what I am proposing to change or, more accurately, try to change. By seeking
> out and bringing together people who do complementary and collaborative work,
> so they can set an example for others.
> This, of course, isn't meant in place of more narrowly defined topical 
> meetings
> and conferences but to be in addition to those.
> James asked the community if we had new ideas and this is a new-ish approach I
> was suggesting.
> Don't get me wrong - I myself will happily continue my efforts in more 
> narrowly
> defined meetings.
> Best wishes,
> Nukri

> On Sun, Jan 29, 2023 at 6:44 PM Pavel Afonine < [ mailto:[email protected] |
> [email protected] ] > wrote:

>> Nukri,

>> IMO, the idea of cross-discipline meetings is great conceptually, at least 
>> for
>> reasons you pointed out, but utopical in practice. When we attend our
>> field-specific meetings we meet colleagues we know, we talk to collaborators
>> from the past or find new ones, we have things in common that we can talk 
>> about
>> to forge something new, we meet authors of papers we were excited to read, 
>> and
>> so on, and so on.
>> I once attended a meeting of some chemistry society, well, which is not too 
>> far
>> from what we are doing, really, as interpreting atomic models is essentially
>> putting your chemistry knowledge into production. And, at that meeting I felt
>> like I'm alone in a dark forest.
>> Now, I imagine, if you bring two (or more) groups of people to your meeting 
>> from
>> two different domains, well, I guess you will end up having two bubbles of
>> people clustered by their field of interest.

>> Same disclaimer goes here as yours -- no offence to any one, just thinking 
>> out
>> loud...

>> All the best!
>> Pavel

>> On Sun, Jan 29, 2023 at 6:09 AM Nukri Sanishvili < [ 
>> mailto:[email protected] |
>> [email protected] ] > wrote:

>>> Hi James,
>>> This meeting has indeed been one of the best ones by its format, content, 
>>> and
>>> atmosphere. Many thanks to all the organizers and attendees of the past.
>>> Nevertheless, it is not surprising that it was cancelled, given the trends 
>>> in
>>> structural biology research. Straightforward evolutionary pressure to adapt 
>>> or
>>> else...

>>> Throughout my career I was always amazed (dare I say, annoyed?) how 
>>> scientists
>>> from different fields, or even the same field but different methods, speak
>>> different languages. How little they understand each other, become 
>>> entrenched
>>> in their own methods and how much of the collaboration/cooperation
>>> opportunities are wasted.

>>> IMO, having a conference on "Complementary Methods in Structural Biology" 
>>> with
>>> the emphasis on complementarity and not on individual methods, would be a 
>>> great
>>> benefit in the long run. Hopefully it would give good examples to young
>>> researchers to help them develop a collaborative mindset.

>>> If I offended anyone, it was not intentional, I promise, and apologize in
>>> advance.
>>> Best wishes to all and best of luck to all who continue the effort for the
>>> benefit of the whole community.
>>> Nukri

>>> On Fri, Dec 16, 2022 at 4:11 PM James Holton < [ mailto:[email protected] |
>>> [email protected] ] > wrote:

>>>> I want to thank everyone who attended the 2022 Gordon Research
>>>> Conference and Gordon Research Seminar on Diffraction Methods in
>>>> Structural Biology, as well as all those who contributed to these great
>>>> gatherings in the past. It was an outstanding meeting if I do say so
>>>> myself. Not just because it had been so long without in-person
>>>> interaction, not just because we had zero covid cases (which I see as no
>>>> small feat of Mind over Virus), but because of this amazing community.
>>>> It is rare in this world to have such a strong spirit of collaboration,
>>>> camaraderie and openness in undertakings as high-impact as this.
>>>> Surmounting the barriers to atomic-detail imaging of biological systems
>>>> has never been more exciting and more relevant. I am proud to be a part
>>>> of it, and honored to have served as Chair.

>>>> It is therefore with heavy heart that I report to this community that I
>>>> was the last Chair of the Diffraction Methods GRC.

>>>> The GRC Conference Evaluation Committee
>>>> ( [ https://www.grc.org/about/conference-evaluation-committee/ |
>>>> https://www.grc.org/about/conference-evaluation-committee/ ] ) voted this
>>>> year to discontinue the Diffraction Methods GRC and GRS. This ends a
>>>> 46-year tradition that I feel played a vital, and vibrant role in the
>>>> work of the people who answer questions on this BB. The reason given
>>>> was insufficient attendance. All other metrics, such as evaluation
>>>> surveys and demographics were very strong. I have tried to appeal, but
>>>> I'm told the vote was unanimous and final. I understand that like so
>>>> many conference organizing bodies the GRC is having to make tough
>>>> financial decisions. I must say I disagree with this one, but it was not
>>>> my decision to make.

>>>> Many of the past and elected Chairs have been gathering and discussing
>>>> how to replace the Diffraction Methods GRC/GRS going forward. Many great
>>>> ideas, advice and perspectives have been provided, but that is a select
>>>> group. I feel it is now time to open up this discussion to the broader
>>>> community of structural methods developers and practitioners. There are
>>>> some important questions to ask:

>>>> * How do we define this community?
>>>> Yes, many of us do cryoEM too, but is that one methods meeting?
>>>> or two?
>>>> * Does this community need a new diffraction methods meeting?
>>>> As in one meeting or zero?
>>>> * Should we merge with an existing meeting?
>>>> It would make logistics easier, but a typical GRC has 22 hours
>>>> of in-depth presentations over 5 days. The GRS is 7 hours over 2 days.
>>>> As Chair, I found that was not nearly enough.
>>>> * Where do you think structural methods are going?
>>>> I think I know, but I may be biased.
>>>> * Should the name change?
>>>> From 1976 to 2000, it was "Diffraction Methods in Molecular
>>>> Biology". The word "diffraction", BTW, comes from the Latin for
>>>> "shattering of rays", and originally used to describe the iridescence of
>>>> bird feathers. That's spectroscopy!
>>>> How about:
>>>> "Structural Methods for the Departing of Rays"

>>>> I'm sure there are many more questions, and better suggestions. I look
>>>> forward to enlightening discussions! GRCs have always been about
>>>> discussion, and I hope to keep that tradition alive in this community.

>>>> -James Holton
>>>> MAD Scientist

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