Dear colleagues,

My lab is looking for a Research Officer (Postdoc) to strengthen our team in 
the Ubiquitin Signalling Division at WEHI in Melbourne, Australia.

We aim to understand the structure and molecular mechanisms of E3 ubiquitin 
ligases, their basic biology, and roles in human diseases such as cancer, 
inflammatory conditions, and neurodegeneration. In the past years, our lab has 
gained deep insights into the mechanisms and structures of several E3 ubiquitin 
ligase complexes using X-ray crystallography (Lechtenberg et al., Nature 2016; 
Cotton et al., Mol. Cell 2022; Wang, Cotton et al., Nat. Comms. 2023; Cotton & 
Lechtenberg, Biochem. Soc. Trans., 2020). We now want to expand on these 
efforts, further integrating cryo-electron microscopy.

We offer a vibrant, multi-disciplinary and highly collaborative environment at 
the forefront of ubiquitin research and structural biology with ready and 
regular access to state-of-the-art biophysics (SEC-MALS, ITC, SPR) and 
structural biology equipment incl. cryo-EM (Titan Krios G4 with Falcon 4 direct 
detector at the Bio21/WEHI Ian Holmes Imaging Centre), automated 
crystallisation, synchrotron (Australian Synchrotron) and NMR facilities.

Applicants should possess a PhD in a relevant discipline, a demonstrated track 
record of 1st author publications in peer reviewed journals in structural 
biology and strong practical experience in protein biochemistry and structural 
biology (cryo-EM or crystallography).

More information and application details here:
https://wehi.wd3.myworkdayjobs.com/en-US/WEHI/job/Research-Officer---Structural-Biology-of-E3-Ubiquitin-Ligases_JR1578-3

Application closing date:  27 Feb 2023 (AEST)

The start date is flexible. Pre-application enquiries are welcome and 
encouraged. Please email me at 
lechtenber...@wehi.edu.au<mailto:lechtenber...@wehi.edu.au>.

Best wishes,
Bernhard
Bernhard C. Lechtenberg PhD
NHMRC Emerging Leadership Fellow
Laboratory Head
Ubiquitin Signalling Division​​​​​​​​​​​​​​
E lechtenber...@wehi.edu.au<mailto:lechtenber...@wehi.edu.au>
T +61 3 9345 2217


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